Contact: Alexander Shtifman
Phone: 617-713-8989
alex...@childrens.harvard.edu

Congratulations to Dr. Jun Hu, who has each been awarded a post-doctoral fellowship from the Cancer Research Institute (CRI).
Jun Jacob Hu, a postdoctoral fellow in the Hao Wu lab, will use high-throughput screening, biochemical characterization and structural studies to identify potential inhibitors against Gasdermin D (GSDMD). Gasdermin D is a recently identified downstream effector of inflammasomes. This project will provide significant insight into the regulation mechanism of the pore-forming activity of GSDMD in pyroptotic cell death and may lead to new therapeutic strategies for disease treatment.