Contact: Alexander Shtifman
Phone: 617-713-8989
alex...@childrens.harvard.edu

Congratulations to Jianbin Ruan and Lan Jiang, who were awarded a post-doctoral fellowships from the Charles A. King Trust.

Jianbin Ruan Ph.D., a postdoctoral fellow in the Wu lab, will investigate the role of gasdermin (GSDMD) family of proteins in formation of membrane pores inn inflammasome-induced pyroptotic cell death. 

Lan Jiang Ph.D., a postdoctoral fellow in the Zhang lab demonstrated that differential histone H3K27 tri-methylation (H3K27me3) in the two alleles underlies a novel imprinting mechanism, which is independent of DNA methylation. He will further investigate this by defining and functionally validating the imprinting control region using integrated analysis of allelic H3K27me3, chromatin accessibility, transcriptome, and CRISPR-based epigenome editing.