Contact: Alexander Shtifman
Phone: 617-713-8989

Dr. Li, a postdoctoral fellow in the Springer lab, will test the hypothesis that the conformational ensemble of integrin α5β1 specifies its function, and rational perturbation of its ensemble with conformation-selective antibody or small molecules can convert its role from protumoral to a tumor-inhibiting, and even eradicate dormant breast cancer cells that are resistant to traditional therapies.