The wear and tear of life takes a cumulative toll on our bodies. Our organs gradually stiffen through fibrosis, which is a process that deposits tough collagen in our body tissue. Fibrosis happens little by little, each time we experience illness or injury. Eventually, this causes our health to decline.
"As we age, we typically accumulate more fibrosis and our organs become dysfunctional," says Denisa Wagner, PhD, the Edwin Cohn Professor of Pediatrics in the Program in Cellular and Molecular Medicine and a member of the Division of Hematology/Oncology at Boston Children's Hospital and Harvard Medical School.
Ironically, fibrosis can… Read Full Article »
Harvard Stem Cell Institute (HSCI) researchers at Massachusetts General(MGH) and Boston Children’s hospitals (BCH) for the first time have used a relatively new gene-editing technique to create what could prove to be an effective technique for blocking HIV from invading and destroying patients’ immune… Read Full Article »
We all remember Dolly the sheep, the first mammal to be born through a cloning technique called somatic cell nuclear transfer (SCNT). As with the thousands of other SCNT-cloned animals ranging from mice to mules, researchers created Dolly… Read Full Article »
Roughly a year ago we told you about Yi Zhang, PhD - a stem cell biologist in Boston Children's Hospital's Program in Cellular and Molecular Medicine - and his efforts to make a cloning technique called somatic cell… Read Full Article »
BOSTON, Oct. 22, 2015 /PRNewswire-USNewswire/ -- A study of where and how an enzyme cuts DNA may have inadvertently revealed a basic principle of gene regulation, say researchers in Boston Children's Hospital's Program in Cellular and Molecular Medicine… Read Full Article »
Researchers in the laboratory of Frederick Alt of the Howard Hughes Medical Institute and Program in Cellular and Molecular Medicine (PCMM) at Children's Hospital Boston have made important strides towards resolving a long-standing question about how different classes… Read Full Article »