Kirchhausen Lab
Tomas Kirchhausen, Ph.D.
Senior Investigator, PCMM at Boston Children’s Hospital
Professor of Cell Biology and Professor of Pediatrics, Harvard Medical School
Director, Harvard Medical School-Portugal Program in Translational Research and Information
- Contact Information
- Office Phone: 617.713.8888
- Fax: 617.713.8898
- Email: kirc...@crystal.harvard.edu
- Administrative Assistant
- Catherine McDonald
- Phone: 617.713.8889
- Email: Cath...@childrens.harvard.edu
Publications
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Publications from “2006”
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Structure determination of clathrin coats to subnanometer resolution by single particle cryo-electron microscopy
Fotin, A.; Kirchhausen, T.; Grigorieff, N.; Harrison, S. C.; Walz, T.; Cheng, Y.
J Struct Biol (2006), Volume: 156, Issue: 3, Pages: 453-60 -
Secramine inhibits Cdc42-dependent functions in cells and Cdc42 activation in vitro
Pelish, H. E.; Peterson, J. R.; Salvarezza, S. B.; Rodriguez-Boulan, E.; Chen, J. L.; Stamnes, M.; Macia, E.; Feng, Y.; Shair, M. D.; Kirchhausen, T.
Nat Chem Biol (2006), Volume: 2, Issue: 1, Pages: 39-46 -
Macropinocytosis: regulated coordination of endocytic and exocytic membrane traffic events
Falcone, S.; Cocucci, E.; Podini, P.; Kirchhausen, T.; Clementi, E.; Meldolesi, J.
J Cell Sci (2006), Volume: 119, Issue: Pt 22, Pages: 4758-69 -
Inhibition of dynamin completely blocks compensatory synaptic vesicle endocytosis
Newton, A. J.; Kirchhausen, T.; Murthy, V. N.
Proc Natl Acad Sci (2006), Volume: 103, Issue: 47, Pages: 17955-60 -
Role of lipids and actin in the formation of clathrin-coated pits
Boucrot, E.; Saffarian, S.; Massol, R.; Kirchhausen, T.; Ehrlich, M.
Exp Cell (2006), Volume: 312, Issue: 20, Pages: 4036-48 -
Synthesis of a 10,000-membered library of molecules resembling carpanone and discovery of vesicular traffic inhibitors
Goess, B. C.; Hannoush, R. N.; Chan, L. K.; Kirchhausen, T.; Shair, M. D.
J Am Chem (2006), Volume: 128, Issue: 16, Pages: 5391-403 -
Large scale synthesis of the Cdc42 inhibitor secramine A and its inhibition of cell spreading
Xu, B.; Pelish, H.; Kirchhausen, T.; Hammond, G. B.
Org Biomol (2006), Volume: 4, Issue: 22, Pages: 4149-57 -
The Cdc42 inhibitor secramine B prevents cAMP-induced K+ conductance in intestinal epithelial cells
Pelish, H. E.; Ciesla, W.; Tanaka, N.; Reddy, K.; Shair, M. D.; Kirchhausen, T.; Lencer, W. I.
Biochem Pharmacol (2006), Volume: 71, Issue: 12, Pages: 1720-6 -
A burst of auxilin recruitment determines the onset of clathrin-coated vesicle uncoating
Massol, R. H.; Boll, W.; Griffin, A. M.; Kirchhausen, T.
Proc Natl Acad Sci (2006), Volume: 103, Issue: 27, Pages: 10265-70 -
Dynasore, a cell-permeable inhibitor of dynamin
Macia, E.; Ehrlich, M.; Massol, R.; Boucrot, E.; Brunner, C.; Kirchhausen, T.
Dev Cell (2006), Volume: 10, Issue: 6, Pages: 839-50
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Areas of Research
Learn more about research at the IDI by exploring our areas of research below:
