Alper Lab
Chester A. Alper, M.D.
Senior Investigator, PCMM at Boston Children’s Hospital
Professor, Department of Pediatrics, Harvard Medical School
- Contact Information
- Office Phone: 617.713.8850
- Lab Phone: 617.713.8850
- Email: alp...@idi.harvard.edu
Publications
Featured Publications
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A genetic explanation for the rising incidence of type 1 diabetes, a polygenic disease
Awdeh, Z. L.; Yunis, E. J.; Audeh, M. J.; Fici, D.; Pugliese, A.; Larsen, C. E.; Alper, C. A.
J Autoimmun (2006), Volume: 27, Issue: 3, Pages: 174-81 -
Incomplete penetrance of susceptibility genes for MHC-determined immunoglobulin deficiencies in monozygotic twins discordant for
Alper, C. A.; Husain, Z.; Larsen, C. E.; Dubey, D. P.; Stein, R.; Day, C.; Baker, A.; Beyan, H.; Hawa, M.; Ola, T. O.; Leslie, R. D.
J Autoimmun (2006), Volume: 27, Issue: 2, Pages: 89-95 -
Increased apoptosis of CD20+ IgA+ B cells is the basis for IgA deficiency: the molecular mechanism for correction in vitro by IL
Husain, Z.; Holodick, N.; Day, C.; Szymanski, I.; Alper, C. A.
J Clin Immunol (2006), Volume: 26, Issue: 2, Pages: 113-25 -
The haplotype structure of the human major histocompatibility complex
Alper, C. A.; Larsen, C. E.; Dubey, D. P.; Awdeh, Z. L.; Fici, D. A.; Yunis, E. J.
Hum Immunol (2006), Volume: 67, Issue: 1-2, Pages: 73-84 -
Mendelian inheritance of polygenic diseases: a hypothetical basis for increasing incidence
Awdeh, Z. L.; Alper, C. A.
Med Hypotheses (2005), Volume: 64, Issue: 3, Pages: 495-8 -
The genetics of HLA-associated disease
Larsen, C. E.; Alper, C. A.
Curr Opin Immunol (2004), Volume: 16, Issue: 5, Pages: 660-7 -
CD2 engagement induces dendritic cell activation: implications for immune surveillance and T-cell activation
Crawford, K.; Stark, A.; Kitchens, B.; Sternheim, K.; Pantazopoulos, V.; Triantafellow, E.; Wang, Z.; Vasir, V.; Larsen, C. E.; Gabuzda, D.; Reinherz, E.; Alper, C. A.
Blood (2003), Volume: 102, Issue: 5, Pages: 1745-52 -
Inheritable variable sizes of DNA stretches in the human MHC: conserved extended haplotypes and their fragments or blocks
Yunis, E. J.; Larsen, C. E.; Fernandez-Viña, M.; Awdeh, Z. L.; Romero, T.; Hansen, J. A.; Alper, C. A.
Tissue Antigens (2003), Volume: 62, Issue: 1, Pages: 1-20 -
Extended HLA/complement allele haplotypes: Evidence for T/t-like complex in man
Awdeh, Z. L.; Raum, D.; Yunis, E. J.; Alper, C. A.
Proc Natl Acad Sci USA (1983), Volume: 80, Issue: 1, Pages: 259-63
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Areas of Research
Learn more about research at the IDI by exploring our areas of research below:
