Immune Disease Institute

Hi-Fi-Sci - Music & Science Animation

Hey Music & Science lovers, help us bring together the work of composers & scientists in a unique, ambitious multimedia event!

Caught on Film

Latest news article by Jake Miller entitled "Single-molecule movies capture the chaotic origins of dynamic assembly in cells" published August 2, 2012 in the Harvard Medical School website. The Latest news article describes the findings by Ema Cocucci and Francois Aguet which appeared in the August 3, 2012 issue of Cell.

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The first moments in the life of a clathrin-coated pit

Clathrin-mediated endocytosis August 2012

This molecular animation made collaboratively by Janet Iwasa and Tom Kirchhausen shows a 3D simulation of how coated vesicles form in real time, including features of numerous experimentally-derived atomic structures, cellular dynamics and molecular interactions.

3D simulation of how endocytic clathrin coated vesicles form, 2012 (Tom Kirchhausen and Janet Iwasa)

The Animators of Life

The New York Times, November 15, 2010 - By ERIK OLSEN - Technology - 1147 words

The Animators of Life by Erik Olsen, NYT , November 2010

Nuclear envelope starts with a clean sheet, JCB podcast August 2011

Human Pit

Formation of a clathrin coated pit performed by a group of students attending the Cellular and Molecular Biology of Membranes advance course held between June 8 and June 19, 2009 in Cargese, France.

Clathrin-mediated endocytosis September 2008

This animation shows the process of clathrin-mediated endocytosis of transferrin receptors, focusing on the assembly and disassembly of the clathrin cage

3D simulation of how endocytic clathrin coated vesicles form, 2008 (Tom Kirchhausen and Janet Iwasa)

The birth of a clathrin coat

3D Simulation of how a Clathrin Coat forms (Tom Kirchhausen and Allison Bruce) 2000

The birth of a clathrin coat

Sec23p/24p Complex of COPII

X-ray structure of the terminal domain of clathrin, Ter Haar, Musacchio, Harrison & Kirchhausen Cell 1998

Live-cell imaging of Clathrin-coated pit and coated vesicles formation

AP-2 labeled with sigma (symbol)2-EGFP w/ Voice Description,Erlich et al Cell 2004

Fluorescent LDL as a probe to identify single-endocytic clathrin-coated pits/vesicles

Clathrin labeled with EGFP-LCa and LDL labeled with DiI w/ Voice Description

Fluorescent reovirus as a probe to identify single-endocytic, Ehrlich et Cell 2004

Endocytosed (a)

Endocytosed (b)

Non-Endocytosed

Dnm1p localization and mitochondria constrictions and fissions, Legesse-Miller et al MBoC 2003

4D Dnm1p and mitochondria constrictions and fission

3D yeast mitochondria in the absense of Dnm1p

3D yeast mitochondria in the presence of Dnm1p

IlLUSTRATIONS

SELECTED MAGAZINE COVERS

Cell

CMLS

JCB

Current Opinion in Immunology

Immunity

Nature Structural & Molecular Biology

Nature

Molecular Biology of the Cell

Current Biology

Molecular Biology of the Cell

Nature

Lab Photo Gallery

Goodbye lunch for Kati

Lab Photo Gallery 2012

Steeve's Farewell

TK BDay