Investigators
Areas of Research
Learn more about our research by exploring our areas of research below:
A great variety of path-breaking research is being done in our 19 distinct investigator-led laboratories.
Our labs are led by world-class senior investigators who are esteemed in their research fields, and by ambitious junior investigators whose bold work represents the future of biomedical research.
Click on the separate areas below to learn more about the investigators and the research they pursue with great dedication.
- Chester A. Alper, M.D.
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The Alper lab studies the genetics of complex (polygenic) disease in humans, with a focus on autoimmunity, particularly within the…
- Frederick Alt, Ph.D.
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Frederick Alt and his colleagues study the molecular mechanisms involved in the somatic assembly and modification of antigen receptor genes…
- Michael C. Carroll, Ph.D.
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The Carroll lab is interested in understanding the role of the complement system in innate and acquired immunity and how it…
- Alvin Davis, M.D.
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The Davis lab researches the complement proteins of the immune system and their crucial role in the progression of hereditary angioedema…
- Anne Goldfeld, M.D.
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The Goldfeld laboratory focuses on the…
- Sun Hur, Ph.D.
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Correct discrimination of "self" vs "non-self" nucleic acids by the innate immune system is essential for host defense against viral infection.…
- Tomas Kirchhausen, Ph.D.
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Our research focuses on the processes that mediate and regulate the movement of membrane proteins throughout cells. In particular we study the…
- Judy Lieberman, M.D., Ph.D.
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The Lieberman lab studies cytotoxic T lymphocytes (CTL) that are key cells in the immune defense against viral infection and cancer.
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- Klaus Rajewsky, M.D.
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The Rajewsky lab has explored how B lymphocytes develop from stem cells in the bone marrow of the mouse into…
- Anjana Rao, Ph.D.
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The Rao lab is studying the mechanisms by which T cells turn on genes when they respond to foreign antigens. When…
- Eileen Remold, Ph.D.
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Neutrophils and Pulmonary Infection
The Remold-O’Donnell Laboratory studies the role of SerpinB1 in protecting the host defenses of the lung against microbial…
- Derrick Rossi, Ph.D.
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The unique ability of stem cells to perpetuate themselves through self-renewal, and to give rise to mature effector cell types in a…
- Motomu Shimaoka, M.D., Ph.D.
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The Shimaoka lab is interested in the underlying mechanism by which the activity of cell adhesion molecule integrins…
- Leslie Silberstein, M.D.
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A long-term objective of Dr. Silberstein’s research laboratory is to better define niche-induced signals and their intracellular pathways controlling HSPC…
- Timothy Springer, Ph.D.
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Adhesion molecules on lymphocytes and leukocytes regulate cell interactions in development, antigen recognition, homing, and inflammation. The Springer lab focuses on integrins,…
- Ulrich von Andrian, M.D., Ph.D.
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Research in the von Andrian lab seeks answers to the question how circulating blood cells find their way in the body.
Directed…
- Denisa D. Wagner, Ph.D.
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The Wagner lab studies how blood cells respond rapidly to injury or stressful situations and initiate defensive or reparatory processes. Specifically, they…
- Florian Winau, M.D.
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The Winau lab studies diverse aspects of antigen presentation, a process pivotal for activation of T-lymphocytes. Winau and colleagues investigate three principal…
